Curcumin, commonly called diferuloyl methane, is a hydrophobic polyphenol derived from the rhizome (turmeric) of the herb Curcuma longa which is a member of the ginger family (Zingiberaceae). Turmeric has been used traditionally for many ailments because of its wide spectrum of pharmacological activities. Curcumin is believed to be the most bioactive and soothing portion of the herb turmeric. Curcumin has antioxidant, anti-inflammatory, antiviral and antifungal actions. Studies have shown that curcumin is not toxic to humans. Turmeric (95 % curcumin) is effective in reducing post-surgical inflammation. It helps to prevent atherosclerosis by reducing the formation of bloods clumps.
CURCUBEST is a proprietary product from Vidya Herbs, with enhanced bioavailability. CURCUBEST is an organic turmeric extract with over 95 % curcuminoids and bioenhancers. At Vidya Herbs, we have evaluated the pharmacokinetics of CURCUBEST in preclinical models. Increased absorption of curcumin in the formulation prompted us to test the bioavailability in healthy human subjects. The increased bioavailability could be attributed to the non-curcuminoid components such as turmerones.
The presence of α- and aromatic turmerones significantly increases the amount of curcumin transported into the cells. α-turmerone inhibits the activity of P-gp, a drug efflux pump. Pgp have been proven to have a very important role in inhibiting efficient drug entry into the systemic circulation. P-gp pumps drug molecules back out of cells with the help of changing ATP to ADP. This can lead to drug resistance. Turmerones in CURCUBEST acts as inhibitors that might block the action of P-gp by taking away its ATP or by competing with the drug for the pump, so less curcumin is pumped out.
CURCUBEST is proven to be safe upon oral consumption as evident from our toxicity studies in preclinical models. Further, during the human clinical studies, no adverse events were reported. CURCUBEST is available as per stringent quality control.
Contains curcuminoids such as curcumin (diferuloylmethane), demethoxycurcumin, and bisdemethoxycurcumin
Free radical mediated
Useful against skin infections; Treat boils efficiently
Protects skin from the damaging effects of UV B radiation
Reduce formation of wrinkles on the skin; anti-ageing
Helps reducing inflammation, hepatic disorders
Works as Anti oxidants
Composition : Each Tablet contains Extract of Haridra (Curcuma longa)*(Rz) 500mg
Indications & Usage : Cytoprotective , Anti- Oxidant.